AUTOLOGOUS PLATELET-RICH PLASMA THERAPY IN HYPERTROPHIC GINGIVITIS OF PREGNANCY: CASE-BASED THESIS

Abstract

Hypertrophic gingivitis of pregnancy (HGP) is a common complication associated
with hormonal shifts, microbiome imbalance, and inadequate oral hygiene. Standard
treatment with antibiotics may negatively affect fetal development, which necessitates the
search for safer alternatives. Autologous platelet-rich plasma (APR) therapy has been
shown to possess anti-inflammatory, regenerative, and antibacterial effects without systemic
adverse reactions. This paper highlights a clinical case of severe HGP managed with APR
therapy after delivery. The results confirm APR as a safe, minimally invasive, and effective
therapeutic approach. Its application may improve periodontal health during pregnancy
and reduce risks of adverse maternal and fetal outcomes.