SELECTED LABORATORY PARAMETERS FOR COVID-19-ASSOCIATED ASEPTIC NECROSIS OF THE HIP JOINT IN MILITARY PERSONNEL

Abstract

Aseptic necrosis of the femoral head (avascular, ischemic necrosis) is a disabling
disease caused by insufficient blood supply to the subchondral region of the femoral
head. Osteonecrosis is sometimes called "coronary disease of the hip," since the essence
of the disease is similar to heart damage of ischemic origin. One of the main causes of
avascular necrosis is COVID-19 [1, 2]. Aseptic necrosis of the femoral head is the cause
of hip replacement in 5-12% of patients undergoing hip arthroplasty and is an important
problem, imposing a huge economic and social burden on patients and the government
[4, 5]. COVID-19-associated aseptic necrosis, in addition to clinical manifestations, is
accompanied by changes in biochemical parameters and blood coagulation parameters.
Available scientific sources contain a certain amount of information that with the
development of osteonecrosis, changes in certain laboratory parameters in the blood are
observed. The severity of laboratory changes is statistically correlated with the degree of
osteonecrosis of the femoral head [3].