EPIDEMIOLOGICAL FEATURES OF OPPORTUNISTIC VIRAL INFECTIONS AFTER ORTHOTOPIC LIVER TRANSPLANTATION.

Authors

  • D.R. Abdurakhimova
  • R.I. Kasimova
  • R.H. Zhuraev
  • N.G. Kan

Keywords:

opportunistic viral infections, liver transplantation, cytomegalovirus, EpsteinBarr virus, herpes simplex virus.

Abstract

Opportunistic viral infections are common in liver transplant recipients. We know
that there is a risk of infection with cytomegalovirus (CMV) and herpes simplex viruses-
1 and 2 (HSV-1 and 2), Epstein-Barr virus (EBV) reactivation of infection and recurrence
of infection. Of the above infections, cytomegalovirus (CMV) is one of the most common
and serious opportunistic infections in patients with solid organ transplantation. In
different series, the incidence of CMV infection ranges from 25% to 85%. The indirect
effect of infection includes a decrease in the long-term survival of the patient and the
allograft. The advantages of cytomegalovirus (CMV) prevention in preventing the direct
consequences of CMV infection and disease are well known; however, the effect of
exposure to antiviral agents on preventing the indirect consequences of CMV infection
is poorly defined.

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Published

2022-10-13